Patient History

A 29-year-old man with no history of fever underwent a weight loss of 14 kgs in the previous 5 months presents with a history of nonproductive cough. There was no history of fever. 

In addition, he had had moderate exertional dyspnea, asthenia, adynamia, and weight loss of about 14 kgs in the previous 5 months. Being a patient with an acute respiratory condition and suspicion of COVID-19, real-time PCR (RT-PCR) was used to confirm a SARS-CoV-2 infection from a nasopharyngeal swab.

Laboratory Investigations

At the time of hospital admission, the patient showed:

  • Absence of leukocytosis
  • Mild neutrophilia (80%) and marked lymphopenia (4.1%), and mild anemia (9.9 g/dL) without alterations in the platelet series.
  • C-reactive protein was increased (184.7 mg/L), 
  • Ferritin was elevated (> 2,000 ng/dL)
  • D-dimer reached 4,600 ng/mL, and procalcitonin was 5.76 ng/mL
  • Respiratory frequency was 35.
  • Oxygen saturation was less than 90%. 
  • Outpatient sputum analysis: positive for infection with Mycobacterium tuberculosis without resistance to rifampicin
  • Routine evaluation with confirmatory tests showed coinfection with HIV, with a viral load of 78,100 copies/mL and a CD3/4+ level of 133 C/µL.

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