A 58-year-old man with a 15-year history of type 2 diabetes, presents with progressive fatigue and swelling in his legs. Despite adherence to his diabetes medication, his recent HbA1c was 8.5%. Laboratory tests reveal elevated serum creatinine and significant proteinuria. Ultrasound of the kidneys shows increased echogenicity consistent with chronic kidney disease.What would be the correct direction of treatment to rule out other possibilites

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Dr. U N

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The diagnosis in this case is diabetic nephropathy, which is a serious complication of diabetes that affects the kidneys. Further investigation required includes a renal biopsy to confirm the diagnosis and assess the extent of kidney damage.

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