Case of Langerhans cell h...

A man in his 50s diagnosed with Langerhans cell histiocytosis presented with a history of hypertension, cranial diabetes insipidus (DI), subclavian stenosis, and spinal stenosis. The patient was found to have acquired refractory hypertension seven years after receiving the original diagnosis of cutaneous LCH. A rheumatology referral was made when CT imaging was used to explore refractory hypertension and found abnormalities suggestive of aortitis, including arterial wall thickening and bilateral renal artery stenosis. In addition, both arms' blood pressure (BP) increased during the assessment. The right arm’s blood pressure was 180/110 mm Hg, while the left was 140/100 mm Hg. Despite receiving medical therapy with bisoprolol 10 mg daily, amlodipine 5 mg daily, doxazosin 8 mg daily, and minoxidil 400 mg daily, the patient's blood pressure remained high.