Craniofacial morphea, enc...

Craniofacial morphea, encompassing conditions like Parry-Romberg Syndrome and en coup de sabre, results in tissue damage, including skin, fat, muscle, cartilage, and bone. Onset typically occurs between 5 and 15 years, with early involvement indicating a worse prognosis. While its exact cause is not fully understood, craniofacial morphea is considered inflammatory, and immunomodulatory medications can halt its progression. Mirror imaging compares facial halves at a single point, showcasing asymmetry while tracking heat maps over time reveals disease progression, and overlaying 3D facial images from different periods is feasible.