Erythematous rash

A 25-year-old man visited our clinic complaining of rashes on the right thigh. He had been engaged in chemical experiments, and 12 days before the visit (hereafter referred to as day 0), he had spilt alkyl bromide on his right thigh. On day 1–2, erythema with tiny vesicles had appeared on the thigh, and on around day 7, he had complained of fever and vomiting, and the erythema had spread over the trunk. He had visited a dermatologist nearby and then had been referred to our clinic (on day 12).

 

He presented uncircumscribed erythema on his right thigh. The erythema on the trunk had disappeared by this time. At the same time, we noticed that several warts on his left palm, which he had suffered from for years in spite of multiple cryotherapies, had turned brownish. Histological analysis of the right thigh revealed massive infiltration of lymphocytes and vacuolar changes of the epidermis. Topical steroid (clobetasol propionate) ointment was prescribed. The rashes on the thighs had disappeared by the visit on day 21, and by his next visit on day 50, all the VV on the palm had resolved.