Normal TSH, High total T4, normal FT4, normal total T3 and FT3  IS seen in:

A) BIOTIN interference
B) Familial dysalbuminemic hyperthyroxinemia
C) Thyroid binding globulin deficiency
D) Resistance to thyroid hormone

 

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Dr. Lal Chand

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It's Biotin interference. Biotin is added as reagent in lab for estimating T4 and T3 levels, sometimes these hormones get attached to Biotin and false high LEVELS are detected. In all other options Thyroid hormone carriers like albumins, tyhroglobulin are less and defective, can' can't carry hormone from gland to blood and from blood to tissues

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