A 67-year-old male was presented to the clinic with worsening myalgia and weakness in his shoulders and lower limbs, resulting in reduced mobility. In addition, he had an H/o severe COPD and ischemic heart disease. On examination, proximal myopathy was noted (MRC Grade 4/5) with hip flexion and extension weakness and shoulder abduction and adduction (MRC Grade 4+/5). 

Regular medication included simvastatin 80 mg daily. On investigation, the patient had started clarithromycin 250 mg daily for one month. It was prescribed on a prophylactic basis to reduce COPD exacerbations.

Laboratory investigations revealed a creatine kinase level of 62-109, AST 20-36, ALT 11-45, creatinine 63 and potassium 4.4. The patient's condition got complicated by hyperkalaemia (7.4 mmol/L), requiring repeated treatment with insulin/dextrose and calcium. In addition, calcium gluconate was administered for cardio-stabilization. These reports confirmed the Rhabdomyolysis condition.

 

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