A 7-year-old male child, the 1st of twin delivery from a non-consanguineous marriage, presented with yellowish discoloration of the eyes for 1 year and abdominal distension for 8 months. The jaundice was insidious in onset, gradually progressive, and accompanied by high-coloured urine without clay-coloured stools or itching. He experienced three episodes of jaundice in the past year, each preceded by low-grade fever and resolving with oral medications. Abdominal distension, involving the upper abdomen, developed gradually over the last 8 months without any relieving or aggravating factors. Notably, there is a history of a previous sibling's death due to a serious liver disorder. Antenatal history revealed a normal twin pregnancy with adequate supplements and TT injections, while birth history indicated full-term vaginal delivery with low birth weight but no neonatal complications. Considering the recurrent jaundice, progressive abdominal distension, and significant family history, what is the likely diagnosis, and what investigations and treatment plan would be appropriate?
 

  • #pediatrics
  • #critical care
  • #gastroenterology
  • #family health
  • #endo-diabetology
  • #emergency medicine
  • #general medicine
  • #diagnostics
  • #pharmacology

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Dr. U N Sahoo

Dr. U N Sahoo

General Medicine Specialist

· Bhubaneswar

Biliary atresia; therefore, perform the following investigations: 1) LFT 2) USG 3) Serum ceruloplasmin 4) Hepatitis panel 5) Autoimmune markers - (ANA, SMA, LKM) 6) Liver biopsy

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