A 55-year-old woman has been diagnosed with diabetic nephropathy after having a history of T2DM for 12 years. Upon evaluation, the glomerular filtration rate was 50 ml/min, with creatinine level be 2.1%. T2DM was managed with glimepiride 3 mg/day. Currently, her HbA1c was 6.7%. The patient also had recurrent UTI history and now has developed mild non-proliferative diabetic retinopathy in both eyes. The physician now believes in starting an alternate therapy in the patient for better management of comorbidities. The patient refuses to use Insulin therapy.
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