A 5-week-old child appears with quickly growing, flat-topped red papules on the left side of her face. A magnetic resonance imaging (MRI)/magnetic resonance angiography (MRA) and echocardiography of the head and neck were performed. The presence of a massive segmental facial infantile hemangioma (IH) should raise suspicions of PHACE (posterior fossa brain malformation, hemangiomas of the face, arterial anomalies, cardiac anomalies, and eye abnormalities) syndrome.

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