A 86-year-old woman presented with a large neck mass and a 6-week history of increasing dysphonia, stridor, and left-sided otalgia.

Examination

On examination, there was a firm 2&times;3 cm left-sided level III neck mass with no overlying skin changes. Flexible fiberoptic nasolaryngoscopy revealed a large exophytic mass with complete airway obstruction. CT scan of the neck revealed the mass to measure approximately 3.3&times;3.7&times;3.1 cm. It was shown to involve her left supraglottic larynx and extend down to at least the level of her glottis Pathology of the node revealed large atypical cells, Reed&ndash;Sternberg cells, and a fine reticular sclerosis pattern. Immunophenotyping performed on a paraffin block demonstrated positive staining of the large atypical cells with cluster of differentiation (CD) 15 and CD30. The stains were negative for leukocyte common antigen (LCA), CD20, EBV-encoded small ribonucleic acid (RNA) (EBER).&nbsp;

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MediSage Case Discussions

Explore the case of an 86-year-old woman with a neck mass, dysphonia, and airway obstruction, revealing Reed-Sternberg cells in pathology.

Neck Mass Diagnosis in an 86-Year-Old Woman

Neck mass with otalgia

Clinical case discussion shared for educational purposes and professional medical opinion.