Seizures & Neuroganglioma

A 52-year-old man with type 2 diabetes had a history of focal and generalized seizures due to a neuroganglioma. Despite having the neuroganglioma resected, he still experienced recurrent seizures. The patient was on insulin therapy. He became highly motivated to control his disease better and embarked on a regular, vigorous exercise program relatively recently. This resulted in a dramatic fall in blood glucose and enabled him to reduce his insulin doses, but he was detecting more frequent hypoglycaemia in the afternoon by SMBG. As the seizures tended to recur during days 16–19 of the month, he wore the sensor during that time. The glucose levels dropped between 1 a.m. and 6 a.m. and went undetected by SMBG. Table 1 displays his medications and recent laboratory findings. The goals of CGMS, in this case, were to determine whether there was a relationship between the patient’s seizures and hypoglycaemia and to assess his afternoon glucose patterns in relationship to his exercise.