A 26-year-old male patient visited the clinic with complaints of severe burning sensation during urination and dysuria for four days. Additionally, he was suffering from penile discharge and testicular tenderness. He had H/o multiple heterosexual relationships before 8days. He also had knee, joint, and ankle pain for two weeks. In addition, he had irritation and redness in the eye with conjunctivitis.

On physical examination, his vital signs were typical. There was mucopurulent cloudy discharge from the urethra. Swollen testicles were also observed. Following counselling, urethral and ocular swabs and blood samples were aseptically obtained and tested. It showed a different pattern confirming that pathogenesis was due to two different strains of a microorganism, which might contribute to the early appearance of arthritis symptoms. As shown in the figure, susceptibility testing was done using the Kirby-Bauer diffusion method. Therefore, a diagnosis of urethritis was made, and a dual therapy was initiated with gentamicin and azithromycin to treat the multi-drug resistant infection.

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