An 8-year-old boy presented with polyuria, polydipsia, abdominal pain, and urinary incontinence one and half a month prior to admission. Physical examination revealed a typical flattened face, especially the bridge of the nose. Almond-shaped eyes that slant up. A short neck, small ears, a tongue that tends to stick out of the mouth, tiny white spots on the iris (coloured part) of the eye, tachycardia, small hands, feet, and face. Thyroid glands were not palpable. Laboratory data revealed diabetic ketoacidosis with plasma glucose: 860 mg/dl. He had thyroid hyperfunction with TSH: < 0.1 microU/ml, T3: 219.7 ng/dl, T4: 15 micrograms/dl. Thyroid autoimmune antibodies were also increased. There was markedly increased radiotracer uptake in the bilateral thyroid glands in Tc-99 thyroid scan.
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