Transient Hyperinsulinism...

Transient Hyperinsulinism (THI), a prominent cause of recurrent neonatal hypoglycemia, often self-resolves but may necessitate treatment. It is linked to unknown causes and risk factors like birth asphyxia, prematurity, maternal diabetes, and abnormal gestational weight. Early diagnosis and intervention in the neonatal phase are crucial due to severe hypoglycemia. Initial management centres on maintaining normoglycemia through increased glucose administration, progressing to intravenous glucagon infusions. Long-term therapy involves diazoxide as the primary treatment for THI or somatostatin analogues in cases of diazoxide non-responsiveness.