A bacterium-derived, cancer-associated immunopeptidome

The immune system is endowed with the capacity to combat alien invaders including bacterial species and to eliminate endogenous deviants such as transformed cells. In this context, much attention has been paid to the possibility that bacterial and tumor antigens may be cross-reactive, explaining how the composition of the microbiota influences cancer immunosurveillance. In an interesting twist, a recent Nature paper by Kalaora et al. describes the identification of intracellular bacteria...