Parity and Mortality Risk in Women: The Role of Depression

The study investigated the association between parity and mortality, along with the mediating role of depression, The analysis included 16,962 women and revealed that nulliparous women had higher all-cause and cause-specific mortality rates compared to those with one to three live births, who showed a 17% and 33% reduction in all-cause and cancer mortality, respectively. Women with more than four live births had reduced all-cause mortality and mortality from other diseases. Depression partially mediated the relationship between parity and mortality outcomes. No significant association was found between parity and cardiovascular disease mortality.