Evaluation of neuroretinal integrity in optical coherence tomography‐graded eyes with partial‐thickness macular holes

To evaluate neuroretinal integrity in different subtypes of optical coherence tomography (OCT)‐graded partial‐thickness macular holes. Lamellar macular hole, ERMF and MPH were diagnosed in 33 (47%), 31 (43%) and 7 (10%) eyes with a VA of 0.18 ± 0.25, 0.15 ± 0.2, and 0.06 ± 0.08 (p = 0.323), respectively. Median follow‐up time was 11 (interquartile range 4–32.5), 10 (interquartile range 5–18) and 19 (interquartile range 8–24) months in LMH, ERMF and MPH. In all subgroups, VA remained stable during the follow‐up (p = 0.652, p = 0.915 and p = 1.000). Epiretinal proliferations (EP) were present in 12 LMH and 3 ERMF. At baseline, eyes with EP had significantly worse VA (p < 0.001), wider foveal cavities (p = 0.007) and thinner foveal floors (p < 0.001) compared with eyes without EP. Twelve out of 15 eyes with EP showed exudative cystoid spaces. Among all 71 eyes, 51 remained morphologically and functionally stable during follow‐up. In the present study cohort, EP are associated with worse VA and advanced neuroretinal tissue loss presenting with wider foveal cavities and thinner foveal floors. During the follow‐up period, VA remained stable in all entities of partial‐thickness macular holes.