Hematospermia is rarely associated with urologic malignancy: Analysis of United States claims data

Hematospermia is an alarming symptom and can cause significant patient distress, but work‐up is often negative. To characterize the clinical evaluation of hematospermia and its association with the diagnosis of urologic malignancy. A small minority of patients with benign hematospermia were later diagnosed with urologic cancer in a large nationally representative sample. Therefore, after excluding hematuria with urinalysis, physicians should conservatively manage and reassure patients with hematospermia, especially those under 40 years of age.