Metformin in Pregnancy: Benefits Clear, Long-Term Effects Uncertain

Metformin is commonly used during pregnancy to manage type 2 diabetes, PCOS, and gestational diabetes, offering benefits like reduced hypoglycemia risk and lower costs. While generally considered safe, concerns persist about long-term effects on offspring, including potential impacts on growth, metabolism, and cognition. Current evidence is limited and inconsistent, highlighting the need for well-designed, long-term studies to clarify metformin’s true safety profile during pregnancy.