OPHTHALMOLOGY

This article reports the recent prevalence of diabetic retinopathy (DR) and diabetic macular oedema (DME) in American Indian and Alaska Natives (AI/AN) served by the Indian Health Services’ (IHS) teleophthalmology program, as identified using ultrawide field imaging (UWFI). This was a retrospective analysis of 2016–2019 clinical data (n = 53,900). Patients averaged 56 years of age with a 68 mmol/mol A1c, and 55% had had diabetes for 5+ years. The AI/AN have a high burden of diabetes and its complications. The IHS is resource-constrained, making accurate disease estimates necessary for resource allocation and budget justifications to Congress. These data update the forecast of diabetic eye disease in Indian Country and suggest that UWFI identifies early DR.

Prevalence of Diabetic Retinopathy and Diabetic Macular Edema in American Indian and Alaska Natives: Insights from IHS Teleophthalmology Program

NEUROLOGY

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GYNAECOLOGY - IVF

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Early Pregnancy Cannabis Use Linked to Higher Risk of Preterm Birth

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PEDIATRICS

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CARDIOLOGY

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ENDO-DIABETOLOGY

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GASTROENTEROLOGY

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MCI Studies Show Major Variation in Treatment Outcome Reporting

An umbrella review of 153 studies involving adults with mild cognitive impairment (MCI) identified 143 unique treatment outcomes. Global cognition was the only outcome reported in more than half of studies, while two-thirds of outcomes appeared in three or fewer studies. The substantial heterogeneity in outcome reporting may limit evidence synthesis and treatment evaluation.

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Varenicline Nasal Spray Improves Dry Eye Disease Symptoms and Signs

A prospective placebo-controlled study of 50 patients with dry eye disease found that twice-daily varenicline nasal spray significantly improved symptoms and ocular surface staining after 28 days compared with vehicle. Improvements were greater in dry eye questionnaire and dryness scores, as well as corneal and conjunctival staining. No serious adverse events were reported.

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Risk Factors Linked to Delayed Epithelial Healing After Keratoplasty

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Monofocal Aspheric IOL Shows Favorable 12-Month Cataract Outcomes

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NGS Improves Diagnostic Accuracy for Malignant Biliary Strictures

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Prevalence of Diabetic Ey...

Prevalence of Diabetic Eye Diseases in American Indians and Alaska Natives (AI/AN) as Identified by the Indian Health Service’s National Teleophthalmology Program Using Ultrawide Field Imaging (UWFI)